The prospects for enhancing traditional treatment of alcoholism, addiction, and relapse through pharmaceuticals have never been more promising.

Through the generous support of individual, corporate, and public donors, The Scripps Research Institute has already made major strides toward understanding and treating alcoholism and addiction.

• TSRI researchers have identified a large part of the neurocircuitry involved in the reinforcing action of alcohol.
• They have begun to identify how this circuitry changes when a person transitions from social drinking to alcohol abuse and dependence.
• They have established several working laboratory models that mimic this transition for use in preclinical and clinical studies of efficacy of potential therapeutics.
• They have developed the infrastructure to conduct clinical trials for developing ground-breaking therapies for alcoholism and addiction.