The Pearson Center Laboratories - Yesterday
Candice Contet's Yesterday
Since its inception in 2011, the Contet laboratory has been investigating how proteins known to be modulated by ethanol in vitro may contribute to the behavioral effects of alcohol in vivo. This line of research revealed a key role for G-protein-gated inwardly rectifying potassium (GIRK) channels in binge drinking and implicated large conductance, calcium- and voltage-activated potassium (BK) channels in the behavioral adaptations triggered by chronic exposure to alcohol, such as tolerance to intoxication and drinking escalation.
Olivier George's Yesterday
The George lab has made seminal contributions to the field including: discovering a novel population of neurons in the brain of humans, rats and mice that are involved in nicotine dependence, identifying neuronal ensembles responsible for nicotine and alcohol addiction, and unveiled the cellular and molecular changes associates with long term use of nicotine, cocaine, methamphetamine and alcohol use on the brain.
Remi Martin-Fardon's Yesterday
Research in the Martin-Fardon laboratory is involved in programs aimed at identifying new pharmacological targets for relapse prevention, a challenging factor in the treatment of post-dependent individuals. These studies have identified the hypocretin system as being one of the systems recruited by drugs of abuse
Courtney Miller's Yesterday
The Miller Laboratory discovered that memories associated with methamphetamine use can be selectively “erased” with a single treatment of a compound targeting actin.
Marisa Roberto's Yesterday
The Roberto Lab has made seminal contributions to the addiction field, by identifying cellular and synaptic adaptations associated with alcohol and other drugs, and understanding the underlying mechanisms involved in stress and anxiety induced drug seeking.
Michael Taffe's Yesterday
The Taffe Laboratory showed that cannabidiol, a non-psychoactive compound in marijuana, can ward off some of the memory-impairing effects of acute intoxication with Δ9-tetrahydrocannabinol, recommending a possible harm-reducing regulatory step as States decide to legalize recreational marijuana.